Home > Knowledge > Content
CLL chromosome and gene abnormality detection probe
- Aug 15, 2018 -
About CLL

Chronic lymphocytic leukemia (CLL) is a mature B lymphocyte clonal proliferative tumor characterized by accumulation of lymphocytes in peripheral blood, bone marrow, spleen and lymph nodes. Peripheral blood B lymphocyte clinical diagnosis duration (3 months) ≥ 5 × 109 / L (such as peripheral blood B cells <5 × 109 / L with bone marrow infiltration caused by cytopenia or disease-related symptoms are also diagnosed as chronic lymph Cellular leukemia. About 80% of patients with chronic lymphocytic leukemia have detected chromosomal abnormalities by fluorescence in situ hybridization. The most common deletion is chromosome 13 long arm del (13q14.1); chromosome 12 deletion or trisomy; short arm 17 The stain is deficient in del (17p).