Product Description: multiple myeloma
Applications: Hematological tumor
1q21 gene probe
1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour.
2.Accuracy: Less non-specific background staining (dyeing). Increase difficult samples detection rate.
3.Reproducibility: Different laboratories test results are highly reproducible.
The 1q21 gene amplification detection probe uses an orange-red fluorescent dye to label 1q21 region, and the 1q21 probe can be bound to the target detection site by in situ hybridization. This method is used to detect the abnormal status of multiple myeloma genes, and provide reference for the identification, prognosis and drug use of clinical leukemia patients.
1q21 (CKS1B) is the most common genetic abnormality in MM. The amplification of CKS1B gene leads to the up-regulation of cell cycle, which causes many proliferative diseases. 1q21 amplification is often associated with the infiltrating phenotype of MM, with poor prognosis and rapid disease progression.