BCL2/IGH T (14;18) Fusion Probe

BCL2/IGH T (14;18) Fusion Probe

Product Description:lymphoma
Applications: Hematological tumor

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Product Details

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BCL2/IGH t(14;18) gene fusion probe


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                                    BCL2/IGH


Product Advantages

1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour.

2.Accuracy: Less non-specific background staining (dyeing). Increase difficult samples detection rate.

3.Reproducibility: Different laboratories test results are highly reproducible. 

 

◆Probe Description

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The two probes can be combined with the target detection site ,using an orange-red dye labeled BCL2 gene and a green dye labeled IGH gene.


◆Clinical Significance

The t(14;18) translocation occurred in 85% of follicular lymphoma (FL) and 1/3 of diffuse lymphoma (DL) with a poor prognosis. Studies have shown that BCL2/IGH translocation rearrangement plays a role in stimulating B lymphocyte hyperproliferation. The incidence of most translocations in patients with non-Hodgkin's lymphoma is significantly higher than that in healthy controls.

  

◆Size Specifications

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