CBFB/MYH11 Fusion Probe

CBFB/MYH11 Fusion Probe

Product Description: acute myeloid leukemia/AML(Non APL)
Applications: hematological tumor

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Product Details

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CBFB/MYH11 gene fusion probe



Technology

image.pngdo not contain Repetitive Sequence result in:


  • High specificity - Does not bind to non-target fragments .

  • High sensitivity - Effective detection of small fragments .

  • Strong fluorescent signal - Not obscured by background color and probe signal .

  • Fluorescent background and noise are low - Not easy to mask weak signals .



 

◆Probe Description

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The CBFB probe was labeled with orange-red dye, and the MYH11 probe was labeled with green dye. The two probes were combined to the target detection site by in situ hybridization. 


◆Clinical Significance

The CBFB/MYH11 gene fusion can be used for the diagnosis of AML. In addition, for the CBFB/MYH11 gene positive fusion case, the detection of the fusion gene is also the most valuable indicator for the determination of the treatment plan and the evaluation of the efficacy, such as CBFB. Quantitative analysis of the /MYH11 fusion gene can also be used to judge the level of leukemia cells in patients, the detection of minimal residual disease and the risk of recurrence. Patients with AML patients with CBFB/MYH11 gene fusion have a better prognosis, and high DFS and low recurrence rates can be achieved with HDAC.

 

◆Size Specifications

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