IGH Break Apart Probe
Product Description: lymphoma
Applications: Lymphatic hematopoietic system tumor
IGH break apart rearrangement probe
1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour.
2.Accuracy: Less non-specific background staining (dyeing). Increase difficult samples detection rate.
3.Reproducibility: Different laboratories test results are highly reproducible.
IGH is a dual color break probe, which is composed of two probes directly labeled at 14q32.33, in which the probe labeled with orange red dye is hybridized to the proximal end of the IGH gene, and the probe labeled with green dye is hybridized with the distal end of the IGH gene.
IGH gene breaks and translocation types are complex, involving a variety of genes and common in ALL/MM/ lymphoma. It can be used to detect the abnormal and minimal residual focus of IGH gene, and IGH gene break can be used as a marker of malignant cloning of myeloma cells. It is not affected by clinical stages and immune types. It can be used as one of the powerful basis for diagnosis of MM.